Compound FK506 is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and inflammatory response mediated by FK506 limit its usefulness. In this study, the protective effect of Korean Red Ginseng (KRG) against FK-506-induced damage in LLC-PK1 pig kidney epithelial cells was investigated.

UVB-exposed keratinocytes secrete various paracrine factors. Among these factors, basic fibroblast growth factor (bFGF) stimulates the proliferation of melanocytes. Ginsenosides, the major active compounds of ginseng, are known to have broad pharmacological effects. In this study, we examined the anti-proliferative effects of ginsenosides on bFGF-induced melanocyte proliferation.

Heat processed ginseng, Sun ginseng (SG), has been reported to have improved therapeutic properties compared to raw forms, such as increased efficiencies of anti-diabetic, anti-inflammatory, and anti-hyperglycemic effects. The aim of the present study was to investigate the anti-obesity effects of SG through the suppression of cell differentiation and proliferation of mouse 3T3-L1 preadipocyte cells and the lipid accumulation in Caenorhabditis elegans (C. elegans).