Effect of Korean Red Ginseng extract on colorectal lung metastasis through inhibiting the epithelial-mesenchymal transition via TGF-β1/Smads signaling-mediated Snail/E-cadherin expression

In colorectal cancer (CRC), 40–60% of patients develop metastasis. The epithelial-mesenchymal transition (EMT) is a pivotal and intricate process that increases the metastatic potential of CRC. The aim of this study was to investigate the effect of Korean red ginseng extract (RGE) on colorectal metastasis through inhibiting of EMT and the metastatic abilities of CRC cells.