Ginseng is known to have anti-apoptotic, anti-inflammatory and anti-oxidant effects. The present study investigated a possible role of Korean Red Ginseng (KRG) in suppressing dopaminergic neuronal cell death and the cleavage of p35 to p25 in substantia nigra (SN) and striatum (ST) using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease mouse model.
Micromorphology and development of epicuticular structure on epidermal cell of ginseng leaves
A leaf cuticle has different structures and functions in barrier for water loss and in protection from various environmental stresses.
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Anti-breast cancer activity of Fine Black ginseng ( Meyer) and ginsenoside Rg5
This study was conducted to evaluate the anti-cancer activity of Fine Black ginseng (Panax ginseng Meyer, FBG BF) and its main component, Rg5, in MCF-7 (HER2-/ER+) breast cancer cells. Cell viability was determined by MTT assay. Action mechanisms were performed by cell cycle assay, Annexin V apoptosis assay and western blot analysis. FBG BF showed cytotoxicity in breast cancer cells in a dose-dependent manner. MTT assay showed that MCF-7 and MDA-MB-453 cell proliferations were inhibited by Rg5 treatment for 24, 48 and 72 hr in a dose-dependent manner.
