Abnormal changes in skin color induce significant cosmetic problems and affect quality of life. There are two groups of abnormal change in skin color; hyperpigmentation and hypopigmentation. Hyperpimentation, darkening skin color by excessive pigmentation, usually are major concerns Asian people with yellow brown skin. A variety of hypopigmenting agents have been used, but the treating hyperpigmented condition is still challenging and the results are often discouraging. Panax ginseng has been used traditionally in eastern Asia to treat various diseases, due to its immunomodulatory, neuroprotective, antioxidative, and anti-tumor activities.

Though the aerial parts of hydroponic Panax ginseng are reported to contain higher contents of total ginsenosides than those of roots, the isolation and identification of active metabolites from the aerial parts of hydroponic P. ginseng hasn’t been carried out so far.

Korean Ginseng (KG) is an ethnopharmacologically valuable herbal plant with various biological properties including anti-cancer, anti-atherosclerosis, anti-diabetic, and anti-inflammatory activities. Since there is currently no drug or therapeutic remedy derived from KG, we developed a ginsenoside-enriched fraction (AP-SF) for prevention of various inflammatory symptoms.

Ginseng, the root of Panax ginseng (PG), has been used widely as a herbal medicine for the prevention and treatment of various diseases. PG had pharmacological effects on neurodegenerative diseases such as Alzheimer’s disease (AD). The present study was designed to evaluate the neuroprotective effects of PG and the possible neuroprotective mechanisms in advanced glycation end products (AGEs)-induced AD model rats.

Adipocytes, which are the main cellular component of adipose tissue, are the building blocks of obesity. The nuclear hormone receptor PPARγ is a major regulator of adipocyte differentiation and development. Obesity, which is one of the most dangerous yet silent diseases of all time, is fast becoming a critical area of research focus.

Ginseng is known to have anti-apoptotic, anti-inflammatory and anti-oxidant effects. The present study investigated a possible role of Korean Red Ginseng (KRG) in suppressing dopaminergic neuronal cell death and the cleavage of p35 to p25 in substantia nigra (SN) and striatum (ST) using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced Parkinson’s disease mouse model.

A leaf cuticle has different structures and functions in barrier for water loss and in protection from various environmental stresses.

This study was conducted to evaluate the anti-cancer activity of Fine Black ginseng (Panax ginseng Meyer, FBG BF) and its main component, Rg5, in MCF-7 (HER2-/ER+) breast cancer cells. Cell viability was determined by MTT assay. Action mechanisms were performed by cell cycle assay, Annexin V apoptosis assay and western blot analysis. FBG BF showed cytotoxicity in breast cancer cells in a dose-dependent manner. MTT assay showed that MCF-7 and MDA-MB-453 cell proliferations were inhibited by Rg5 treatment for 24, 48 and 72 hr in a dose-dependent manner.