Korean ginseng (Panax ginseng) is one of the most important medicinal plants in the Orient. Among nine cultivars of P. ginseng, Chunpoong commands a much greater market value and has been planted widely in Korea. Chunpoong has superior quality “Chunsam (1st grade ginseng) when made into red ginseng.
Tag Archives: ginseng
Ginsenoside Rg1 suppresses early stage of adipocyte development via activation of CHOP10 in 3T3-L1 and attenuates fat accumulation in high fat diet-induced obese zebrafish
Ginsenoside Rg1 is a class of steroid glycoside and triterpene saponin in Panax ginseng. Many studies suggest that Rg1 suppress adipocyte differentiation in 3T3-L1. However, the detail molecular mechanism of Rg1 on adipogenesis in 3T3-L1 has still not been fully understood yet.
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Effect of Red Ginseng on Cytochrome P450 and P-glycoprotein Activities in Healthy Volunteers
We evaluated the drug interaction profile of red ginseng (RG) with respect to the activities of major cytochrome P450 (CYP) enzymes and the drug transporter P-glycoprotein (P-gp) in healthy Korean volunteers.
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VASP-phosphorylation by ginsenoside Ro inhibits fibrinogen binding to αIIb/β in thrombin-induced human platelets
Glycoprotein IIb/IIIa (αIIb/β3) is involved in platelet adhesion, and triggers a series of intracellular signaling cascade, leading to platelet shape change, granule secretion and clot retraction. In this study, we evaluated the effect of ginsenoside Ro (G-Ro) on the binding of fibrinogen to αIIb/β3.
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Identification of mountain cultivated ginseng and cultivated ginseng using UPLC–oa-TOF MSE with a Multivariate Statistical Sample Profiling Strategy
The mountain cultivated ginseng (MCG) and cultivated ginseng (CG) both belong to the Panax ginseng, which have similar ingredients. However, their pharmacological activities are obviously different due to the significant differences in growth environment.
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Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue
This study was designed to investigate whether ginsenoside Rb1 (Rb1) and compound K (CK) ameliorated insulin resistance by suppressing endoplasmic reticulum stress (ER stress)-induced inflammation in adipose tissue.
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The Change of ginsenoside composition in the Red ginseng () by the ultrasonication process
The result of USRG-12 indicates that the ultrasonication processed Red ginseng extracts (at 100°C) treated for 12 hrs produced the highest amount of ginsenoside Rg3 (0.803%), Rg5 (0.167%) and Rk1 (0.175%).
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In vitro and in vivo evaluation of Tissue-cultured mountain ginseng on penile erection
Progressed tissue culture techniques have allowed to easily obtain mass product of Tissue-Cultured Mountain Ginseng over 100 years old (TCMG-100). We investigated the effects of TCMG-100 extract on erectile function by in vitro and in vivo studies.
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Effects of gintonin on the proliferation, migration, and tube formation of human umbilical vein endothelial cells: involvement of lysophosphatidic acid receptors and VEGF signaling
Ginseng extracts are known to have angiogenic effects. However, to date, only limited information is available on the molecular mechanism underlying the angiogenic effects and the main components of ginseng that exert these effects. Human umbilical vein endothelial cells (HUVECs) are used as an in vitro model for screening therapeutic agents that promote angiogenesis and wound healing. We recently isolated gintonin, a novel ginseng-derived lysophosphatidic acid (LPA) receptor ligand, from ginseng.
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Assessment of microclimate conditions under artificial shades in a ginseng field
Knowledge on microclimate conditions under artificial shades in a ginseng field would facilitate climate-aware management of ginseng production.
