A refined karyotype based on an ultra-high copy 167-bp tandem repeat and ribosomal DNAs

Panax ginseng Meyer (Asian ginseng) has a large nuclear genome size of over 3.5 Gbp in haploid genome equivalent of 24 chromosomes. Tandem repeats (TRs) occupy significant portions of the genome in many plants and are often found in specific genomic loci, making them a valuable molecular cytogenetic tool in discriminating chromosomes. In an effort to understand the P. ginseng genome structure, we characterized an ultra-high copy 167-bp TR (Pg167TR) and explored its chromosomal distribution as well as its utility for chromosome identification.

Original Source: Journal of Ginseng Research >>

Photoprotective effects of topical ginseng leaf extract using Ultraflo L against UVB-induced skin damage in hairless mice

Abnormal activation of matrix metalloproteinases (MMPs) plays an important role in UV-induced wrinkle formation, which is a major dermatological problem. This formation occurs due to the degeneration of the extracellular matrix (ECM). In this study, we investigated the cutaneous photoprotective effects of ginseng leaf extract treated with Ultraflo L (UTGL) in hairless mice.

Original Source: Journal of Ginseng Research >>

Cytohistological study of the leaf structures of Meyer and L

Both Panax ginseng Meyer and Panax quinquefolius are obligate shade-loving plants whose natural habitats are broadleaved forests of Eastern Asia and North America. Panax species are easily damaged by photoinhibition when they are exposed to high temperatures or insufficient shade. In this study, a cytohistological study of the leaf structures of two of the most well-known Panax species was performed to better understand the physiological processes that limit photosynthesis.

Original Source: Journal of Ginseng Research >>

Korean Red Ginseng water extract arrests growth of xenografted lymphoma cells

Although numerous studies of the anti-cancer activities of Korean Red Ginseng (KRG) have been performed, the therapeutic effect of KRG on leukemia has not been fully elucidated. In this study, we investigated the anti-leukemia activities of KRG and its cellular and molecular mechanisms.

Original Source: Journal of Ginseng Research >>

Fermented ginseng, GBCK25, ameliorates hemodynamic function on experimentally induced myocardial injury

In the present study, we investigated whether treatment with GBCK25 facilitated the recovery of hemodynamic parameters, left ventricle systolic pressure, left ventricular developed pressure, and electrocardiographic changes. GBCK25 significantly prevented the decrease in hemodynamic parameters and ameliorated the electrocardiographic abnormality. These results indicate that GBCK25 has distinct cardioprotective effects in rat heart.

Original Source: Journal of Ginseng Research >>

Induction of Nrf2/ARE-mediated cytoprotective genes by red ginseng oil through ASK1-MKK4/7-JNK and p38 MAPK signaling pathways in HepG2 cells

The induction of cellular defensive genes such as phase II detoxifying and antioxidant enzymes is highly effective strategy for protection against carcinogenesis as well as slowing cancer development. Transcription factor Nrf2 is responsible for the activation of phase II enzymes induced by natural chemopreventive compounds.

Original Source: Journal of Ginseng Research >>

analysis of chemical components induced by steaming between fresh ginseng, steamed ginseng, and red ginseng

The chemical constituents of Panax ginseng were changed by processing methods such as steaming or sun drying. In the present study, in-situ monitoring of steaming induced chemical change of Panax ginseng was performed.

Original Source: Journal of Ginseng Research >>

Endophytic fungi harbored in : diversity and potential as biological control agents against host plant pathogens of root-rot disease

Endophytic fungi play a very important role in balancing the ecosystem and boosting the growth of host. In the present study, we investigated the endophytic fungal diversity of healthy Panax notoginseng and evaluated their potential antimicrobial activity against five major phytopathogens causing root-rot of P. notoginseng.

Original Source: Journal of Ginseng Research >>

Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats

Ginseng essence (GE) is a formulation comprising four medicinal and edible herbs including ginseng (Panax ginseng), American ginseng (Panax quinquefolius), lotus seed (Nelumbo nucifera), and lily bulb (Lilium longiflorum). This study was aimed at investigating the hepatoprotective effect of GE against carbon tetrachloride (CCl4)-induced liver injury in rats.

Original Source: Journal of Ginseng Research >>

Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats

Ginseng essence (GE) is a formulation comprising four medicinal and edible herbs including ginseng (Panax ginseng), American ginseng (Panax quinquefolius), lotus seed (Nelumbo nucifera), and lily bulb (Lilium longiflorum). This study was aimed at investigating the hepatoprotective effect of GE against carbon tetrachloride (CCl4)-induced liver injury in rats.

Original Source: Journal of Ginseng Research >>