Panax ginseng cannot be cultivated on the same land consecutively for an extended time period, and the underlying mechanism regarding microorganisms is still being explored.

Blind and excessive application of fertilizer was found during the cultivation of Panax notoginseng in field, as well as the increase of root rot disease incidence.

Panax ginseng has a wide range of biological activities including anti-inflammatory, antioxidant, and immunomodulatory functions. Wild ginseng cambial meristematic cells (CMCs) were obtained from P. ginseng cambium. This study examined the protective mechanism of wild ginseng CMCs against D-galactosamine (GalN)-induced liver injury. GalN, a well-known hepatotoxicant, causes severe hepatocellular inflammatory damage and clinical features similar to those of human viral hepatitis in experimental animals.

It is not clear whether ginseng affects cyclosporine (CsA)-induced desirable immunosuppressive action. In this study, we evaluated the immunological influence of combined treatment of ginseng with CsA.

Alzheimer’s disease (AD) is a progressive brain disease, for which there is no effective drug therapy at present. Ginsenoside Rg1 (G-Rg1) and Ginsenoside Rg2 (G-Rg2) have been reported to alleviate memory deterioration. However, the mechanism of their anti-AD effect hasn’t yet been clearly elucidated.

The typical drying methods for red ginseng are sun drying and hot-air drying now. The purpose of this study was to investigate drying characteristics of red ginseng by using far-infrared drying.

The beneficial effects of ginsenoside species have been well demonstrated in a number of studies. However, the function of ginsenoside Ro (GRo), an oleanane-type saponin, has not been sufficiently investigated. Thus, the aim of the present study was to investigate the anti-inflammatory effects of GRo in vitro using the Raw 264.7 mouse macrophage cell line treated with lipopolysaccharide (LPS), and to clarify the possible mechanism of GRo involving heme oxygenase-1 (HO-1), which itself plays a critical role in self-defense in the presence of inflammatory stress.

Intracellular Ca2+ ([Ca2+]i) is platelet aggregation-inducing molecule. Therefore, understanding the inhibitory mechanism of [Ca2+]i mobilization is very important to evaluate the antiplatelet effect of a substance. This study was carried out to understand the Ca2+-antagonistic effect of total saponin from Korean red ginseng (KRG-TS).

Ginseng is a semi-shade perennial plant cultivated at sloping, sun-shading area in Korea. Recently, due to air-environmental stress and various fungal diseases, greenhouse cultivation has been suggested as an alternative. However, the optimal light transmission rate (LTR) in the greenhouse has not been established.

This study aims to investigate the effect of decoction process on the change of ginsenosides and relation with anti-proliferative effect in HeLa cells.