Inhibitory effects of [Ca] mobilization by total saponin from Korean red ginseng phosphorylation of PKA catalytic subunit and in human platelets

Intracellular Ca2+ ([Ca2+]i) is platelet aggregation-inducing molecule. Therefore, understanding the inhibitory mechanism of [Ca2+]i mobilization is very important to evaluate the antiplatelet effect of a substance. This study was carried out to understand the Ca2+-antagonistic effect of total saponin from Korean red ginseng (KRG-TS).