Inhibitory mechanism of Korean Red Ginseng on GM-CSF expression in UVB-irradiated keratinocytes

Ultraviolet (UV)-irradiated keratinocytes secrete various proinflammatory cytokines. UV-induced skin damage is mediated by growth factors and proinflammatory cytokines such as granulocyte macrophage colony stimulating factor (GM-CSF). In a previous study, we found that saponin of Korean red ginseng (SKRG) decreased the expression of GM-CSF in UVB-irradiated SP-1 keratinocytes. In this study, we tried to find the inhibitory mechanism of SKRG on UVB-induced GM-CSF expression in SP-1 keratinocytes.

Effect of Korean Red Ginseng treatment on the gene expression profile of diabetic rat retina

Korean Red Ginseng (KRG) is an herbal medicine used in Asian countries and is very popular for its beneficial biological properties. Diabetes mellitus (DM) and its complications are rapidly becoming a global public health concern. The literature on transcriptional changes induced by KRG in rat models of diabetic retinopathy is limited. Considering these facts, we designed this study to determine whether retinopathy-associated genes are altered in DM rat retinas and whether the induced changes are reversed by KRG.

Effect of Korean Red Ginseng treatment on the gene expression profile of diabetic rat retina

Korean Red Ginseng (KRG) is an herbal medicine used in Asian countries and is very popular for its beneficial biological properties. Diabetes mellitus (DM) and its complications are rapidly becoming a global public health concern. The literature on transcriptional changes induced by KRG in rat models of diabetic retinopathy is limited. Considering these facts, we designed this study to determine whether retinopathy-associated genes are altered in DM rat retinas and whether the induced changes are reversed by KRG.