Effect of Korean Red Ginseng treatment on the gene expression profile of diabetic rat retina

Korean Red Ginseng (KRG) is an herbal medicine used in Asian countries and is very popular for its beneficial biological properties. Diabetes mellitus (DM) and its complications are rapidly becoming a global public health concern. The literature on transcriptional changes induced by KRG in rat models of diabetic retinopathy is limited. Considering these facts, we designed this study to determine whether retinopathy-associated genes are altered in DM rat retinas and whether the induced changes are reversed by KRG.