The inhibitory mechanism of crude saponin fraction from Korean Red Ginseng in collagen-induced platelet aggregation

Korean Red Ginseng has been used as a traditional oriental medicine to treat illness and to promote health for several thousand years in Eastern Asia. It is widely accepted that ginseng saponins, ginsenosides, are major active ingredients for Red ginseng’s therapeutic activity against many kinds of illness. Although crude saponin fraction (CSF) displayed anti-platelet activity, the molecular mechanism of its action remains to be elucidated.

Ginsenoside Rd and ischemic stroke; a short review of literatures

Panax ginseng is a well-known economic medical plant which is broadly used in Chinese traditional medicine. This species contains unique class of natural products, namely ginsenosides. Recent clinical and experimental studies lined a plethora of evidences up for the promising role of ginsenosides on different diseases including neurodegenerative, cardiovascular, certain types of cancer, etc. Nowadays, much attention has been paid to ginsenoside Rd as neuroprotective agent to attenuate ischemic stroke damages.

Characteristics of Korean ginseng varieties of Gumpoong, Sunun, Sunpoong, Sunone, Chengsun, and Sunhyang

The Korea Ginseng Corporation (KGC) has developed six varieties of ginseng called Gumpoong, Sunun, Sunpoong, Sunone, Chengsun, and Sunhyang. Gumpoong shows no purple stem in the aerial section and the color of its berries and autumn leaves are distinctively yellow. In the testing of 4-yr old specimens in 2002, the proportions of the below ground roots that were rusty colored for Gumpoong was 1.29 in Daejeon and 1.45 in Eumseong; whereas the proportions for its yellow berry variant landrace were 2.60 and 2.45 in the two regions, respectively.

Chemoprevention of chemical induced skin cancer by root extract

Cancer is emerged as a major health problem globally consequent to increase longevity of the population, changing the environment and life style. Chemoprevention is a new and promising strategy against cancer burden. Recently, some natural products have been identified for their chemopreventive activity for the reduction in cancer incidences. Ginseng is known for its potential to treat various ailments in human beings. The present study was designed to explore the anticancer and anti-oxidative potential of Panax ginseng against chemical induced skin carcinogenesis in mammals.