The inhibitory mechanism of crude saponin fraction from Korean Red Ginseng in collagen-induced platelet aggregation

Korean Red Ginseng has been used as a traditional oriental medicine to treat illness and to promote health for several thousand years in Eastern Asia. It is widely accepted that ginseng saponins, ginsenosides, are major active ingredients for Red ginseng’s therapeutic activity against many kinds of illness. Although crude saponin fraction (CSF) displayed anti-platelet activity, the molecular mechanism of its action remains to be elucidated.