Anti-cancer agents induce a variety of adverse effects when they are administered to cancer patients. Busulfan is a known anti-leukemia agent. When administered for treatment of leukemia in young patients, busulfan could cause damage of the reproductive system as one of its adverse effects, resulting in male sterility.
Daily Archives: 01/23/2015
Red Ginseng extract blocks histamine-dependent itch by inhibition of H1R/TRPV1 pathway in sensory neurons
Korean Red Ginseng – a steamed root of Panax ginseng Meyer – has long been used as a traditional medicine in Asian countries. Its anti-pruritic effect was recently found, but no molecular mechanisms were revealed. Thus, the current study focused on determining the underlying molecular mechanism of Korean Red Ginseng extract (RGE) against histamine-induced itch at the peripheral sensory neuronal level.
Administration of red ginseng ameliorates the memory decline in aged mice
It has been known that ginseng can be applied as a potential nutraceutical for memory impairment, however experiments with animals of old age are few.
Anti-melanogenic effect of ginsenoside Rg3 through ERK-mediated inhibition of microphthalmia-associated transcription factor
Panax ginseng has been used to prolong longevity and is believed to be useful for skin beauty. Ginsenosides are the most active components isolated from ginseng, and ginsenoside Rg3 (G-Rg3) in particular has been demonstrated to possess antioxidative, anti-tumorigenic, and anti-inflammatory effects. The aim of this study was to examine the ability of G-Rg3 to inhibit melanogenesis.