Despite the large number of studies on ginseng, pharmacological activities of ginseng seed oil (GSO) have not been established. GSO is rich in unsaturated fatty acids (UFAs), mostly oleic and linoleic acids. UFAs are known to exert therapeutic effects in non-alcoholic fatty liver disease (NAFLD). In this study, we investigated the protective effect and underlying mechanisms of GSO against NAFLD using in vitro and in vivo models.

Ginseng is a natural product best known for its curative properties in diverse physiological processes such as cancers, neurodegenerative disorders, hypertension and maintenance of hemostasis in the immune system. In previous decades, there have been some promising studies into the pharmacology and chemistry of ginseng components and the relationship between their structure and function. The emerging use of modified ginseng and development of new compounds from ginseng for clinical studies have been a topic of study for many researchers.