In the current phytochemical research on ginseng, the differentiation and structural identification of ginsenosides isomers remain challenging. In this paper, a two-dimensional mass spectrometry (2D-MS) method was developed and combined with statistical analysis for the direct differentiation, identification and relative quantification of protopanaxadiol (PPD)-type ginsenoside isomers.
Monthly Archives: November 2017
Synergistic effect of maclurin on ginsenoside compound K induced inhibition of the transcriptional expression of MMP-1 in HaCaT human keratinocyte cells
The synergistic effect of maclurin on CK-induced inhibition of the transcriptional expression of MMP-1 was investigated in HaCaT human keratinocyte cells. Maclurin suppresses transcriptional expression of MMP-1 via inhibition of ERK/Ets-1 signaling. The combination of CK and maclurin may be promising way to be used as an anti-skin aging agent.
Chemical and bioactive comparison of Panax notoginseng root and rhizome in raw and steamed forms
The root and rhizome are historically and officially utilized as medicinal parts of Panax notoginseng (Burk.) F. H. Chen (PN), which in raw and steamed forms are differently used in practice.
Comparing eight types of ginsenosides in ginseng of different plant ages and regions using RRLC-Q-TOF MS/MS
This article aims to compare and analyze the contents of ginsenosides in ginseng with different plant ages from different localities in China.