Differentiation and identification of ginsenoside structural isomers by two-dimensional mass spectrometry combined with statistical analysis

In the current phytochemical research on ginseng, the differentiation and structural identification of ginsenosides isomers remain challenging. In this paper, a two-dimensional mass spectrometry (2D-MS) method was developed and combined with statistical analysis for the direct differentiation, identification and relative quantification of protopanaxadiol (PPD)-type ginsenoside isomers.