Dammarane-type triterpene oligoglycosides from the leaves and stems of Panax notoginseng and their anti-inflammation activities

Inflammation is widespread in the clinical pathology and closely associated to the progress of many diseases. Triterpenoid saponins as a key group of active ingredients in Panax notoginseng (Burk.) F.H. Chen were demonstrated to show anti-inflammatory effects. However, the chemical structures of saponins in the leaves and stems of Panax notoginseng (PNLS) are still not fully clear. Herein, the isolation, purification and further evaluation of the anti-inflammation activity of dammarane-type triterpenoid saponins from PNLS were conducted.