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An optimized microwave-assisted extraction method for increasing the yields of rare ginsenosides from Panax quinquefolius L

Rare ginsenosides in Panax quinquefolius L. are proved to have stronger bioactivities. The fact that it is hard to obtain large amounts of rare ginsenosides seriously restricts further researches of rare ginsenosides. An easy, fast and efficient method to obtain amounts of different kinds of rare ginsenosides at one time and to quantify precisely of each one is in great need.

Effects of Korean ginseng berry on skin anti-pigmentation and anti-aging via FoxO3a activation

The ginseng berry has various bioactivities, including anti-diabetic, anti-cancer, anti-inflammatory, and anti-oxidative properties. Moreover, we have revealed that the active anti-aging component of the ginseng berry, syringaresinol, has the ability to stimulate longevity via gene activation. Despite the many known beneficial effects of ginseng, its effects on skin aging are poorly understood. In this study, we investigated the effects of ginseng and the ginseng berry on one of the skin aging processes, melanogenesis and age-related pigment lipofuscin accumulation, to elucidate the mechanism of action with respect to anti-aging.

Protective effect of Korean Red Ginseng against FK-506-induced damage in LLC-PK1 cells

Compound FK506 is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and inflammatory response mediated by FK506 limit its usefulness. In this study, the protective effect of Korean Red Ginseng (KRG) against FK-506-induced damage in LLC-PK1 pig kidney epithelial cells was investigated.