The present study investigated the effect of ginseng berry hot water extract (GBx) on blood flow via regulation of lipid metabolites and blood coagulation in rats fed a high-fat diet (HFD).

Ginsenoside Rc (G-Rc) is one of the major protopanaxadiol-type saponins isolated from Panax ginseng, a well-known medicinal herb with many beneficial properties including anti-cancer, anti-inflammatory, anti-obesity, and anti-diabetic effects. In this study, we investigated the effects of G-Rc on inflammatory responses in vitro and examined the mechanisms of these effects.

The American ginseng (Panax. Quinquefolius. L) and Asian ginseng (Panax. ginseng. Meyer) products, such as slices, show similar appearance, but they have significant different prices, leading to wide adulteration in commercial market. Their aroma characteristics are attracting increasing attention and supposed to be effective and non-destructive markers to determine adulteration.

In present study, metabolite profiles of ginsenosides Rk1 and Rg5 from red ginseng or red notoginseng in zebrafish were qualitatively analyzed with the Ultraperformance Liquid Chromatography/Quadrupole -Time-of-Flight Mass Spectrometry, and then we put forward the possible metabolic pathways.

Human skin undergoes distinct changes throughout the aging process, based on both intrinsic and extrinsic factors. In a process called photoaging, UVB irradiation leads to up regulation of MMP-1, which then causes collagen degradation and premature aging. Mixtures of medicinal plants have traditionally been used as drugs in oriental medicine. Based on the previously reported antioxidant properties of Panax ginseng Meyer and Crataegus pinnatifida, we hypothesized that the mixture of Panax ginseng Meyer and Crataegus pinnatifida (GC) would have protective effects against skin aging.

Various Panax ginseng cultivars exhibit range of diversity for morphological and physiological traits. However there is less study on diversity of metabolic profiles and genetic background to understand the complex metabolic pathway in ginseng.

BIOGF1K, a compound K-rich fraction prepared from the root of Panax ginseng is widely applied in cosmetic purpose in Korea. We firstly investigated the functional mechanisms of anti-inflammatory and anti-oxidative activities of BIOGF1K by discovering target enzymes through various molecular studies.

Korean Red Ginseng extract (KRG, Panax ginseng Meyer) and its constituents have been used for the treatment of diabetes. However, it remains unclear whether KRG can enhance the glucose-lowering action of rosiglitazone (ROSI), a peroxisome proliferator-activated receptor gamma synthetic activator, in diet-induced obese mice.

Some differences have been reported in the biotransformation of ginsenosides, probably due to the types of materials used such as ginseng, enzymes, and microorganisms. Moreover, most microorganisms used for transforming ginsenosides do not meet food-grade standards. We investigated the statistical conversion rate of major ginsenosides in ginsenosides model culture (GMC) during fermentation by lactic acid bacteria (LAB) in order to estimate possible pathways.

Ginsenosides are the characteristic and principal components which manifest a variety of the biological and pharmacological activities of the roots and rhizomes of Panax ginseng (GRR). This study was carried out to qualitatively and quantitatively determine the ginsenosides in the cultivated and forest GRR.