Ginsenoside Rc from exerts anti-inflammatory activity by targeting TBK1/IRF-3 and p38/ATF-2

Ginsenoside Rc (G-Rc) is one of the major protopanaxadiol-type saponins isolated from Panax ginseng, a well-known medicinal herb with many beneficial properties including anti-cancer, anti-inflammatory, anti-obesity, and anti-diabetic effects. In this study, we investigated the effects of G-Rc on inflammatory responses in vitro and examined the mechanisms of these effects.