In present study, metabolite profiles of ginsenosides Rk1 and Rg5 from red ginseng or red notoginseng in zebrafish were qualitatively analyzed with the Ultraperformance Liquid Chromatography/Quadrupole -Time-of-Flight Mass Spectrometry, and then we put forward the possible metabolic pathways.

Human skin undergoes distinct changes throughout the aging process, based on both intrinsic and extrinsic factors. In a process called photoaging, UVB irradiation leads to up regulation of MMP-1, which then causes collagen degradation and premature aging. Mixtures of medicinal plants have traditionally been used as drugs in oriental medicine. Based on the previously reported antioxidant properties of Panax ginseng Meyer and Crataegus pinnatifida, we hypothesized that the mixture of Panax ginseng Meyer and Crataegus pinnatifida (GC) would have protective effects against skin aging.

Various Panax ginseng cultivars exhibit range of diversity for morphological and physiological traits. However there is less study on diversity of metabolic profiles and genetic background to understand the complex metabolic pathway in ginseng.

BIOGF1K, a compound K-rich fraction prepared from the root of Panax ginseng is widely applied in cosmetic purpose in Korea. We firstly investigated the functional mechanisms of anti-inflammatory and anti-oxidative activities of BIOGF1K by discovering target enzymes through various molecular studies.

Korean Red Ginseng extract (KRG, Panax ginseng Meyer) and its constituents have been used for the treatment of diabetes. However, it remains unclear whether KRG can enhance the glucose-lowering action of rosiglitazone (ROSI), a peroxisome proliferator-activated receptor gamma synthetic activator, in diet-induced obese mice.