Some differences have been reported in the biotransformation of ginsenosides, probably due to the types of materials used such as ginseng, enzymes, and microorganisms. Moreover, most microorganisms used for transforming ginsenosides do not meet food-grade standards. We investigated the statistical conversion rate of major ginsenosides in ginsenosides model culture (GMC) during fermentation by lactic acid bacteria (LAB) in order to estimate possible pathways.

Ginsenosides are the characteristic and principal components which manifest a variety of the biological and pharmacological activities of the roots and rhizomes of Panax ginseng (GRR). This study was carried out to qualitatively and quantitatively determine the ginsenosides in the cultivated and forest GRR.

Ginsenoside Rd (GSRd), main components of the root of Panax ginseng, exhibit anti-inflammation functions and decrease infarct size in many injuries and ischemia diseases like focal cerebral ischemia. M1 Macrophages are regarded as one of the key inflammatory cells having functions for disease progression.

Korean ginseng (Panax ginseng) one of the well-known medicinal plant of Oriental medicine that is still in practice. A total of 11 Korean ginseng cultivars with unique features to Korean ginseng have been developed until now based on pure line selection method. Among them, a new cultivar namely G-1 with different agricultural traits related to yield and content of ginsenosides was developed in 2012.

Asian ginseng and American ginseng are functional food that share a close genetic relationship and are well-known worldwide. This article aims to investigate the correlation between morphological characteristics and the inherent quality of Asian and American ginsengs.

Panax ginseng Meyer, belonging to the genus Panax of the family Araliaceae, is known for its human immune system-related effects such as immune-boosting effects. Ginseng polysaccharides (GPs) are the responsible ingredient of ginseng in immunomodulation, which are classified as acidic and neutral GPs. Although GPs participate in various immune reactions including the stimulation of immune cells and production of cytokines, the precise function of GPs together with its potential receptor(s) and their signal transduction pathways have remained largely unknown.

Ginsenoside Rg1 is a class of steroid glycoside and triterpene saponin in Panax ginseng. Many studies suggest that Rg1 suppress adipocyte differentiation in 3T3-L1. However, the detail molecular mechanism of Rg1 on adipogenesis in 3T3-L1 has still not been fully understood yet.

Korean ginseng (Panax ginseng) is one of the most important medicinal plants in the Orient. Among nine cultivars of P. ginseng, Chunpoong commands a much greater market value and has been planted widely in Korea. Chunpoong has superior quality “Chunsam (1st grade ginseng) when made into red ginseng.

We evaluated the drug interaction profile of red ginseng (RG) with respect to the activities of major cytochrome P450 (CYP) enzymes and the drug transporter P-glycoprotein (P-gp) in healthy Korean volunteers.