In this study, we screened and identified an endophyte JG09 having strong biocatalytic activity for ginsenosides from Platycodon grandiflorum (P. grandiflorum), converted ginseng total saponins and ginsenoside monomers, determined the source of minor ginsenosides and the transformation pathways, and calculated the maximum production of minor ginsenosides for the conversion of ginsenoside Rb1 to assess the transformation activity of endophyte JG09.
Daily Archives: 12/16/2015
Determination of ginsenosides in Asian and American Ginsengs by liquid chromatography-quadrupole/time of flight-mass spectrometry: assessing variations based on morphological characteristics
Asian ginseng and American ginseng are functional food that share a close genetic relationship and are well-known worldwide. This article aims to investigate the correlation between morphological characteristics and the inherent quality of Asian and American ginsengs.
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Animal lectins: potential receptors for ginseng polysaccharides
Panax ginseng Meyer, belonging to the genus Panax of the family Araliaceae, is known for its human immune system-related effects such as immune-boosting effects. Ginseng polysaccharides (GPs) are the responsible ingredient of ginseng in immunomodulation, which are classified as acidic and neutral GPs. Although GPs participate in various immune reactions including the stimulation of immune cells and production of cytokines, the precise function of GPs together with its potential receptor(s) and their signal transduction pathways have remained largely unknown.
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Ginsenoside Rg1 suppresses early stage of adipocyte development via activation of CHOP10 in 3T3-L1 and attenuates fat accumulation in high fat diet-induced obese zebrafish
Ginsenoside Rg1 is a class of steroid glycoside and triterpene saponin in Panax ginseng. Many studies suggest that Rg1 suppress adipocyte differentiation in 3T3-L1. However, the detail molecular mechanism of Rg1 on adipogenesis in 3T3-L1 has still not been fully understood yet.
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Discrimination of Korean ginseng ( Meyer) cultivar Chunpoong and American ginseng () using the gene
Korean ginseng (Panax ginseng) is one of the most important medicinal plants in the Orient. Among nine cultivars of P. ginseng, Chunpoong commands a much greater market value and has been planted widely in Korea. Chunpoong has superior quality “Chunsam (1st grade ginseng) when made into red ginseng.
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Effect of Red Ginseng on Cytochrome P450 and P-glycoprotein Activities in Healthy Volunteers
We evaluated the drug interaction profile of red ginseng (RG) with respect to the activities of major cytochrome P450 (CYP) enzymes and the drug transporter P-glycoprotein (P-gp) in healthy Korean volunteers.
