Panax vietnamensis Ha et Grushv. or Vietnamese ginseng (VG) is a recently discovered ginseng species. Studies on its chemical constituents have shown that VG is remarkably rich in ginseng saponins, particularly ocotillol saponins. However, the psychopharmacological effects of VG have not been characterized. Thus, in the present study we screened the psychopharmacological activities of VG in mice.

The incidence of halitosis has a prevalence of 22% to 50% throughout the world and is generally caused by anaerobic oral microorganisms, such as Fusobacterium nucleatum, Clostridium perfringens and Porphyromonas gingivalis. Previous investigations on the structure-activity relationships of ginsenosides have led to contrasting results. Particularly, the antibacterial activity of less polar ginsenosides against halitosis-related bacteria has not been reported.

Steaming process of Panax ginseng has been reported to increase its major known bioactive components, ginsenosides, therefore its biological properties compared to regular Panax ginseng. Biological functions of red Panax ginseng attenuating a pro-oxidant environment associated with chronic diseases are of particular interest, since oxidative stress can be a key contributor to the pathogenesis of chronic diseases. In addition, proper utilization of various biomarkers for evaluating antioxidant activities in natural products such as ginseng can also be important providing validity to their activities.

Fermented black ginseng (FBG) is processed ginseng by the repeated heat treatment and fermentation of raw ginseng. The protective effect and mechanism of FBG on cisplatin-induced nephrotoxicity was investigated to evaluate its therapeutic potential.

Ginsenosides are the main pharmacological components of Panax ginseng root, which are thought to be primarily responsible for the suppressing effect on oxidative stress.

The presence of gross deletions in the HIV nef gene (gΔnef) is associated with long-term non-progression of infected patients. Here, we investigated how quickly genetic defects in the nef gene are associated with Korean red ginseng (KRG) intake in 10 long-term slow progressors (LTSPs).

Radiotherapy is one of the most important modalities in cancer treatment; however normal tissue damage is a serious concern. Drug development for the protection or reduction of normal tissue damage is therefore a clinical issue. Herein, we evaluated the protective properties of Panax ginseng Meyer and its corresponding mechanisms.

The prevalence of allergic inflammatory diseases such as atopic dermatitis, asthma, and allergic rhinitis worldwide has increased and complete recovery is difficult. Korean Red Ginseng, which is the heat-processed root of Panax ginseng Meyer, is widely and frequently used as a traditional medicine in East Asia. In this study, we investigated whether Korean Red Ginseng extract (RGE) regulates the expression of proinflammatory cytokines and chemokines via mitogen-activated protein kinases (MAPKs)/NF-κB pathway in allergic inflammation.

Joboksansam, Korean bird wild ginseng, is an artificially cultivated wild ginseng germinated from bird feces. Although numerous pharmacologic activities of wild ginsengs have been reported, the beneficial effect of joboksansam in cancer has not been elucidated. In this study, we investigated the in vivo and in vitro anticancer activities of joboksansam powder.

Korean ginseng, Panax ginseng Meyer (P. ginseng), has been used as a traditional oriental medicine to treat illness and promote health for several thousand years. Ginsenosides are the main constituents for the pharmacological effects of P. ginseng. Since several ginsenosides, including G-Rg3 and G-Rp1, was reported the anti-platelet activity, here we investigated the ability of G-Rp4 to modulate ADP-induced platelet aggregation. The ginsenoside Rp4 (G-Rp4), a similar chemical structure of ginseoside Rp1, was prepared from G-Rg1 by chemical modification.