Panax ginseng is a well-known economic medical plant which is broadly used in Chinese traditional medicine. This species contains unique class of natural products, namely ginsenosides. Recent clinical and experimental studies lined a plethora of evidences up for the promising role of ginsenosides on different diseases including neurodegenerative, cardiovascular, certain types of cancer, etc. Nowadays, much attention has been paid to ginsenoside Rd as neuroprotective agent to attenuate ischemic stroke damages.

Steaming of ginseng is known to change its chemical composition and biological activity. This study was carried out to investigate the effect of different steaming time-scales on chemical constituents and anti-proliferative activity of Vietnamese ginseng (VG).

The Korea Ginseng Corporation (KGC) has developed six varieties of ginseng called Gumpoong, Sunun, Sunpoong, Sunone, Chengsun, and Sunhyang. Gumpoong shows no purple stem in the aerial section and the color of its berries and autumn leaves are distinctively yellow. In the testing of 4-yr old specimens in 2002, the proportions of the below ground roots that were rusty colored for Gumpoong was 1.29 in Daejeon and 1.45 in Eumseong; whereas the proportions for its yellow berry variant landrace were 2.60 and 2.45 in the two regions, respectively.

Cancer is emerged as a major health problem globally consequent to increase longevity of the population, changing the environment and life style. Chemoprevention is a new and promising strategy against cancer burden. Recently, some natural products have been identified for their chemopreventive activity for the reduction in cancer incidences. Ginseng is known for its potential to treat various ailments in human beings. The present study was designed to explore the anticancer and anti-oxidative potential of Panax ginseng against chemical induced skin carcinogenesis in mammals.

It has been known that ginseng can be applied as a potential nutraceutical for memory impairment, however experiments with animals of old age are few.

Korean Red Ginseng – a steamed root of Panax ginseng Meyer – has long been used as a traditional medicine in Asian countries. Its anti-pruritic effect was recently found, but no molecular mechanisms were revealed. Thus, the current study focused on determining the underlying molecular mechanism of Korean Red Ginseng extract (RGE) against histamine-induced itch at the peripheral sensory neuronal level.

Anti-cancer agents induce a variety of adverse effects when they are administered to cancer patients. Busulfan is a known anti-leukemia agent. When administered for treatment of leukemia in young patients, busulfan could cause damage of the reproductive system as one of its adverse effects, resulting in male sterility.

Panax ginseng has been used to prolong longevity and is believed to be useful for skin beauty. Ginsenosides are the most active components isolated from ginseng, and ginsenoside Rg3 (G-Rg3) in particular has been demonstrated to possess antioxidative, anti-tumorigenic, and anti-inflammatory effects. The aim of this study was to examine the ability of G-Rg3 to inhibit melanogenesis.

Colorectal cancer (CRC) is a leading cause of death worldwide. Chronic gut inflammation is recognized as a risk factor for tumor development, including CRC. American ginseng is a very commonly used ginseng species in the West.

Ginseng, a perennial plant belonging to the genus Panax of Araliaceae, is well known for its medicinal properties that help alleviate pathological symptoms, promote health, and prevent potential diseases. Among the active ingredients of ginseng are saponins, most of which are glycosides of triterpenoid aglycones. So far, numerous saponins have been reported as components of Panax ginseng, also known as Korean ginseng. Herein, we summarize available information about 113 saponins related to Panax ginseng; more than 80 of them are isolated from raw or processed ginseng, and the others are acid/base hydrolysates, semi-synthetic saponins, or metabolites.