Although numerous studies of the anti-cancer activities of Korean Red Ginseng (KRG) have been performed, the therapeutic effect of KRG on leukemia has not been fully elucidated. In this study, we investigated the anti-leukemia activities of KRG and its cellular and molecular mechanisms.
Tag Archives: science
Induction of Nrf2/ARE-mediated cytoprotective genes by red ginseng oil through ASK1-MKK4/7-JNK and p38 MAPK signaling pathways in HepG2 cells
The induction of cellular defensive genes such as phase II detoxifying and antioxidant enzymes is highly effective strategy for protection against carcinogenesis as well as slowing cancer development. Transcription factor Nrf2 is responsible for the activation of phase II enzymes induced by natural chemopreventive compounds.
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Fermented ginseng, GBCK25, ameliorates hemodynamic function on experimentally induced myocardial injury
In the present study, we investigated whether treatment with GBCK25 facilitated the recovery of hemodynamic parameters, left ventricle systolic pressure, left ventricular developed pressure, and electrocardiographic changes. GBCK25 significantly prevented the decrease in hemodynamic parameters and ameliorated the electrocardiographic abnormality. These results indicate that GBCK25 has distinct cardioprotective effects in rat heart.
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Endophytic fungi harbored in : diversity and potential as biological control agents against host plant pathogens of root-rot disease
Endophytic fungi play a very important role in balancing the ecosystem and boosting the growth of host. In the present study, we investigated the endophytic fungal diversity of healthy Panax notoginseng and evaluated their potential antimicrobial activity against five major phytopathogens causing root-rot of P. notoginseng.
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analysis of chemical components induced by steaming between fresh ginseng, steamed ginseng, and red ginseng
The chemical constituents of Panax ginseng were changed by processing methods such as steaming or sun drying. In the present study, in-situ monitoring of steaming induced chemical change of Panax ginseng was performed.
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Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats
Ginseng essence (GE) is a formulation comprising four medicinal and edible herbs including ginseng (Panax ginseng), American ginseng (Panax quinquefolius), lotus seed (Nelumbo nucifera), and lily bulb (Lilium longiflorum). This study was aimed at investigating the hepatoprotective effect of GE against carbon tetrachloride (CCl4)-induced liver injury in rats.
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Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats
Ginseng essence (GE) is a formulation comprising four medicinal and edible herbs including ginseng (Panax ginseng), American ginseng (Panax quinquefolius), lotus seed (Nelumbo nucifera), and lily bulb (Lilium longiflorum). This study was aimed at investigating the hepatoprotective effect of GE against carbon tetrachloride (CCl4)-induced liver injury in rats.
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Microbial conversion of major ginsenosides in ginseng total saponins by endophytes
In this study, we screened and identified an endophyte JG09 having strong biocatalytic activity for ginsenosides from Platycodon grandiflorum (P. grandiflorum), converted ginseng total saponins and ginsenoside monomers, determined the source of minor ginsenosides and the transformation pathways, and calculated the maximum production of minor ginsenosides for the conversion of ginsenoside Rb1 to assess the transformation activity of endophyte JG09.
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Ginseng consumption and risk of cancer: a meta-analysis
The findings in currently available research are not consistent with regard to the association between the risk of cancer and ginseng consumption. We aimed to evaluate this association by conducting a meta-analysis of different studies.
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A Single-Center, Randomized, Double-Blind, Placebo-Controlled Study on the Efficacy and Safety of “Enzyme-Treated Red Ginseng Powder Complex (BG11001)” For Anti-Wrinkle and Pro-Elasticity In Subject with Healthy Skin
During the aging process, skin shows visible changes, characterized by a loss of elasticity and the appearance of wrinkles due to reduced collagen production and decreased elasticity of elastin fibers. Panax Ginseng Meyer has been used as a traditional medicine for various diseases due to its wide range of biological activities including skin protective effects. Ginsenosides are the main components responsible for the biological activities of ginseng. However, the protective activities of enzymatic preparation of red ginseng against human skin aging have not been investigated.
