ginseng exerts antidepressant-like effects by suppressing neuroinflammatory response and up-regulating Nrf2 signaling in the amygdala

Depression is one of the most commonly diagnosed neuropsychiatric diseases, but the underlying mechanism and medicine are not well-known. Although Panax (P.) ginseng has been reported to exert protective effects in various neurological studies, little information is available regarding its antidepressant effects.