Effects of cultivation ages and modes on microbial diversity in the rhizosphere soil of

Panax ginseng cannot be cultivated on the same land consecutively for an extended time period, and the underlying mechanism regarding microorganisms is still being explored.

Original Source: Journal of Ginseng Research >>

Optimal fertilizer application for and effect of soil water on root rot disease and saponin contents

Blind and excessive application of fertilizer was found during the cultivation of Panax notoginseng in field, as well as the increase of root rot disease incidence.

Original Source: Journal of Ginseng Research >>

Immunological benefits by ginseng through reciprocal regulation of Th17 and Treg cells during cyclosporine-induced immunosuppression

It is not clear whether ginseng affects cyclosporine (CsA)-induced desirable immunosuppressive action. In this study, we evaluated the immunological influence of combined treatment of ginseng with CsA.

Original Source: Journal of Ginseng Research >>

Protective effect of wild ginseng cambial meristematic cells on D-galactosamine-induced hepatotoxicity in rats

Panax ginseng has a wide range of biological activities including anti-inflammatory, antioxidant, and immunomodulatory functions. Wild ginseng cambial meristematic cells (CMCs) were obtained from P. ginseng cambium. This study examined the protective mechanism of wild ginseng CMCs against D-galactosamine (GalN)-induced liver injury. GalN, a well-known hepatotoxicant, causes severe hepatocellular inflammatory damage and clinical features similar to those of human viral hepatitis in experimental animals.

Original Source: Journal of Ginseng Research >>

A UPLC/MS-based metabolomics investigation of the protective effect of ginsenosides Rg1 and Rg2 in mice with Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive brain disease, for which there is no effective drug therapy at present. Ginsenoside Rg1 (G-Rg1) and Ginsenoside Rg2 (G-Rg2) have been reported to alleviate memory deterioration. However, the mechanism of their anti-AD effect hasn’t yet been clearly elucidated.

Original Source: Journal of Ginseng Research >>