Comparative Phenolic Compounds Profiles and Antioxidative Activity of the Fruit, Leaves, and Roots of Korean Ginseng ( Meyer) According to Cultivation Years

Study on the phenolic compounds profiles and antioxidative activity in ginseng fruit, leaves, and roots depend on the cultivation years have been little reported so far. Hence, this study examined phenolic compounds profiles and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free-radical-scavenging activities in the fruit, leaves, and roots of Korean ginseng (Panax ginseng Meyer) as a function of cultivation years.

Changes in the ginsenoside content during the fermentation process using microbial strains

Red ginseng (RG) is processed from Panax ginseng via several methods including heat treatment, mild acid hydrolysis and microbial conversion to transform the major ginsenosides into minor ginsenosides, which have greater pharmaceutical activities. During the fermentation process using microbial strains in a machine for making red ginseng, a change of composition occurs after heating. Therefore, we confirmed that fermentation had occurred using only microbial strains and evaluated the changes in the ginsenosides and their chemical composition.

Total saponin from Korean red ginseng inhibits binding of adhesive proteins to glycoprotein IIb/IIIa phosphorylation of VASP (Ser) and dephosphorylation of PI3K and Akt

Binding of adhesive proteins (i.e. fibrinogen, fibronectin, vitronectin) to platelet integrin glycoprotein IIb/IIIa (αIIb/β3) by various agonists (thrombin, collagen, ADP) involve in strength of thrombus. This study was carried out to evaluate antiplatelet effect of total saponin from Korean red ginseng (KRG-TS) by investigating whether KRG-TS inhibits thrombin-induced binding of fibrinogen and fibronectin to αIIb/β3.