In the present study, we investigated whether treatment of GBCK25 facilitated the recovery of hemodynamic parameters, left ventricle systolic pressure, left ventricular developed pressure (±dp/dt max) and electrocardiographic changes. GBCK25 significantly prevented the decrease in hemodynamic parameters and ameliorated the electrocardiographic abnormality. These results indicate that GBCK25 has distinct cardioprotectective effects in rat heart.
Monthly Archives: July 2016
An optimized microwave-assisted extraction method for increasing the yields of rare ginsenosides from Panax quinquefolius L
Rare ginsenosides in Panax quinquefolius L. are proved to have stronger bioactivities. The fact that it is hard to obtain large amounts of rare ginsenosides seriously restricts further researches of rare ginsenosides. An easy, fast and efficient method to obtain amounts of different kinds of rare ginsenosides at one time and to quantify precisely of each one is in great need.
Converting panax ginseng DNA and chemical fingerprint into two-dimensional barcode
In this paper, we investigate how to convert Panax ginseng DNA sequence code and chemical fingerprint into two-dimensional code. In order to improve the compression efficiency, GATC2Bytes and DMC algorithms are proposed.
NF-κB- and AP-1-mediated immunostimulatory activity of Compound K in monocytes and macrophages
Compound K (CK) is a bioactive derivative from ginsenoside Rb1 in Panax ginseng (Korean ginseng). Although its biological and pharmacological activities have been studied in various disease conditions, its immunomodulatory role in innate immunity mediated by monocytes/macrophages has been poorly understood.
Molecular differentiation of Russian wild ginseng using mitochondrial nad7 intron3 region
Cultivated ginseng is often introduced as substitute and adulterant of Russian wild ginseng due to its lower cost or misidentification caused by similarity in appearance with wild ginseng. The aim of this study is to develop a simple and reliable method to differentiate Russian wild ginseng from cultivated ginseng.
The interaction of serum albumin with ginsenoside Rh2 (G-Rh2) resulted in the downregulation of G-Rh2 cytotoxicity
Ginsenoside Rh2 (G-Rh2) is a ginseng saponin that is widely investigated because of its remarkable antitumor activity. However, its molecular mechanism by which (20S)G-Rh2 triggers its functions and how target animals avoid its cytotoxic action remains largely unknown.