The impact of fungicide azoxystrobin applied as foliar spray on the physiological and biochemical indices and ginsenosides contents of ginseng was studied in ginseng (Panax ginseng Mey. cv. ‘Ermaya’) under natural environmental conditions. Different concentrations of 25% azoxystrobin SC (150g a.i. /ha and 225 g a.i. /ha) on ginseng plants were sprayed three times and the changes in physiological and biochemical indices and ginsenosides contents of ginseng leaves were tested.