It was previously found that Korean Red Ginseng water extract (KRGE) inhibits histamine-induced itch signaling pathway in peripheral sensory neurons. Thus, in the present study, it was investigated whether KRGE may inhibit another distinctive itch pathway induced by chloroquine (CQ), a representative histamine-independent pathway mediated by MrgrpA3 and TRPA1.
Daily Archives: 05/19/2017
Ginsenoside Rh2 epigenetically regulates cell-mediated immune pathway to inhibit proliferation of MCF-7 breast cancer cells
Ginsenoside Rh2 has been known to enhance the activity of immune cells as well as to inhibit the growth of tumor cells. Although the repertoire of genes regulated by Rh2 is well-known in many cancer cells, the epigenetic regulation has yet to be determined, especially for comprehensive approaches to detect methylation changes.
Influence of phytochemical composition on antioxidant and reducing activities of Indian ginseng [ (L.) Dunal] root extracts
Roots of Withania somnifera (WS) are a celebrated medicinal ingredient in Ayurvedic and many other indigenous systems of medicine. The present study investigates the effect of the phytochemical composition of the extracts on their antioxidant and reducing activities.