Ginseng extracts are known to have angiogenic effects. However, to date, only limited information is available on the molecular mechanism underlying the angiogenic effects and the main components of ginseng that exert these effects. Human umbilical vein endothelial cells (HUVECs) are used as an in vitro model for screening therapeutic agents that promote angiogenesis and wound healing. We recently isolated gintonin, a novel ginseng-derived lysophosphatidic acid (LPA) receptor ligand, from ginseng.
All posts by Sung-Hee Hwang, Byung-Hwan Lee, Sun-Hye Choi, Hyeon-Joong Kim, Kyung Jong Won, Hwan Myung Lee, Hyewon Rhim, Hyoung-Chun Kim, Seung-Yeol Nah
Assessment of microclimate conditions under artificial shades in a ginseng field
Knowledge on microclimate conditions under artificial shades in a ginseng field would facilitate climate-aware management of ginseng production.
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Canola oil is an excellent vehicle for eliminating pesticide residues in aqueous ginseng extract
We previously reported that two-phase partition chromatography between ginseng water extract and soybean oil efficiently eliminated pesticide residues. However, an undesirable odor and an unpalatable taste unique to soybean oil were two major disadvantages of the method. This study was carried out to find an alternative vegetable oil that is cost effective, labor effective and efficient without leaving an undesirable taste and smell.
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Total ginsenosides suppress monocrotaline-induced pulmonary hypertension in rats: involvement of nitric oxide and mitogen-activated protein kinases pathways
Ginsenosides have been shown to exert beneficial pharmacological effects on the central nervous, cardiovascular, endocrine systems. We sought to determine whether total ginsenosides (TG) inhibit monocrotaline (MCT)-induced pulmonary hypertension and to elucidate the underlying mechanism.
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Endophytic YIM PH30019: a promising biocontrol agent with hyperosmolar, mycoparasitism and antagonistic activities of induced volatile organic compounds on root-rot pathogenic fungi of
Biocontrol agents are thought as promising and environmental friendly approaches as agrochemicals for phytodiseases have caused serious environmental and health problems. Trichoderma species have been widely used in suppression of soil-borne pathogens. In this study, an endophytic fungus Trichoderma gamsii YIM PH30019 from healthy Panax notoginseng root was investigated on its biocontrol potential.
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Proteomic analysis reveals that the protective effects of ginsenoside Rb1 are associated with the actin cytoskeleton in -amyloid-treated neuronal cells
The ginsenoside Rb1 (Rb1) is the most abundant compound in the root of Panax ginseng. Recent studies have shown that Rb1 has a neuroprotective effect. However, the mechanisms underlying this effect are still unknown.
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Biological characteristics of GBR-1 involved root rot of stored Korean ginseng
This study aims to describe the characterization of Paenibacillus polymyxa GBR-1 (GBR-1) with respect to its positive and negative effects on the plants.
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Ginseng, the natural effectual antiviral: Protective effects of Korean red ginseng against viral infection
Korean red ginseng (KRG) is a heat-processed ginseng developed by the repeated steaming and air-drying of fresh ginseng. Compared to fresh ginseng, KRG has been shown to possess greater pharmacological activities and stability because of changes that occur in its chemical constituents during the steaming process. In addition to anti-cancer, anti-inflammatory, and immune-modulatory activities, KRG and its purified components have also been shown to possess protective effects against microbial infections.
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Ginseng consumption and risk of cancer: a meta-analysis
The findings in currently available research are not consistent with regard to the association between the risk of cancer and ginseng consumption. We aimed to evaluate this association by conducting a meta-analysis of different studies.
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A Single-Center, Randomized, Double-Blind, Placebo-Controlled Study on the Efficacy and Safety of “Enzyme-Treated Red Ginseng Powder Complex (BG11001)” For Anti-Wrinkle and Pro-Elasticity In Subject with Healthy Skin
During the aging process, skin shows visible changes, characterized by a loss of elasticity and the appearance of wrinkles due to reduced collagen production and decreased elasticity of elastin fibers. Panax Ginseng Meyer has been used as a traditional medicine for various diseases due to its wide range of biological activities including skin protective effects. Ginsenosides are the main components responsible for the biological activities of ginseng. However, the protective activities of enzymatic preparation of red ginseng against human skin aging have not been investigated.
