Tag Archives: ginseng

Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue

This study was designed to investigate whether ginsenoside Rb1 (Rb1) and compound K (CK) ameliorated insulin resistance by suppressing endoplasmic reticulum stress (ER stress)-induced inflammation in adipose tissue.

Original Source: Journal of Ginseng Research >>

The Change of ginsenoside composition in the Red ginseng () by the ultrasonication process

The result of USRG-12 indicates that the ultrasonication processed Red ginseng extracts (at 100°C) treated for 12 hrs produced the highest amount of ginsenoside Rg3 (0.803%), Rg5 (0.167%) and Rk1 (0.175%).

Original Source: Journal of Ginseng Research >>

In vitro and in vivo evaluation of Tissue-cultured mountain ginseng on penile erection

Progressed tissue culture techniques have allowed to easily obtain mass product of Tissue-Cultured Mountain Ginseng over 100 years old (TCMG-100). We investigated the effects of TCMG-100 extract on erectile function by in vitro and in vivo studies.

Original Source: Journal of Ginseng Research >>

Effects of gintonin on the proliferation, migration, and tube formation of human umbilical vein endothelial cells: involvement of lysophosphatidic acid receptors and VEGF signaling

Ginseng extracts are known to have angiogenic effects. However, to date, only limited information is available on the molecular mechanism underlying the angiogenic effects and the main components of ginseng that exert these effects. Human umbilical vein endothelial cells (HUVECs) are used as an in vitro model for screening therapeutic agents that promote angiogenesis and wound healing. We recently isolated gintonin, a novel ginseng-derived lysophosphatidic acid (LPA) receptor ligand, from ginseng.

Original Source: Journal of Ginseng Research >>

Assessment of microclimate conditions under artificial shades in a ginseng field

Knowledge on microclimate conditions under artificial shades in a ginseng field would facilitate climate-aware management of ginseng production.

Original Source: Journal of Ginseng Research >>

Canola oil is an excellent vehicle for eliminating pesticide residues in aqueous ginseng extract

We previously reported that two-phase partition chromatography between ginseng water extract and soybean oil efficiently eliminated pesticide residues. However, an undesirable odor and an unpalatable taste unique to soybean oil were two major disadvantages of the method. This study was carried out to find an alternative vegetable oil that is cost effective, labor effective and efficient without leaving an undesirable taste and smell.

Original Source: Journal of Ginseng Research >>

Total ginsenosides suppress monocrotaline-induced pulmonary hypertension in rats: involvement of nitric oxide and mitogen-activated protein kinases pathways

Ginsenosides have been shown to exert beneficial pharmacological effects on the central nervous, cardiovascular, endocrine systems. We sought to determine whether total ginsenosides (TG) inhibit monocrotaline (MCT)-induced pulmonary hypertension and to elucidate the underlying mechanism.

Original Source: Journal of Ginseng Research >>

Endophytic YIM PH30019: a promising biocontrol agent with hyperosmolar, mycoparasitism and antagonistic activities of induced volatile organic compounds on root-rot pathogenic fungi of

Biocontrol agents are thought as promising and environmental friendly approaches as agrochemicals for phytodiseases have caused serious environmental and health problems. Trichoderma species have been widely used in suppression of soil-borne pathogens. In this study, an endophytic fungus Trichoderma gamsii YIM PH30019 from healthy Panax notoginseng root was investigated on its biocontrol potential.

Original Source: Journal of Ginseng Research >>

Proteomic analysis reveals that the protective effects of ginsenoside Rb1 are associated with the actin cytoskeleton in -amyloid-treated neuronal cells

The ginsenoside Rb1 (Rb1) is the most abundant compound in the root of Panax ginseng. Recent studies have shown that Rb1 has a neuroprotective effect. However, the mechanisms underlying this effect are still unknown.

Original Source: Journal of Ginseng Research >>

Biological characteristics of GBR-1 involved root rot of stored Korean ginseng

This study aims to describe the characterization of Paenibacillus polymyxa GBR-1 (GBR-1) with respect to its positive and negative effects on the plants.

Original Source: Journal of Ginseng Research >>