Ginseng has long been used as a functional food or therapeutic supplement and it is empirically known to be safe and non-toxic. During the past decades or so, a number of in vitro and in vivo experiments, as well as human studies have been conducted to prove the safety of various types of ginseng samples and their components.
Daily Archives: 12/07/2014
Ginsenoside Rb1 ameliorates liver fat accumulation by up-regulating perilipin expression in adipose tissue of db/db obese mice
Ginsenoside Rb1 (G-Rb1), the major active constituent of ginseng, improves insulin sensitivity and exerts anti-diabetic effects. We tested whether the insulin-sensitizing and anti-diabetic effects of G-Rb1 results from a reduction in ectopic fat accumulation, mediated by inhibition of lipolysis in adipocytes.