Beneficial effects of fermented black ginseng and its ginsenoside 20(S)-Rg3 against cisplatin-induced nephrotoxicity in LLC-PK1 cells

Nephrotoxicity is a common side effect of medications. Panax ginseng is one of the best-known herbal medicines and its individual constituents enhance renal function. Identification of its efficacy and mechanisms of action against drug-induced nephrotoxicity as well as the specific constituents mediating this effect have recently emerged as an interesting research area focusing on the kidney-protective efficacy of P. ginseng.