All posts by Tae Ho Chung, Chul Park, In Hag Choi

Effects of Korean Red Ginseng marc with aluminum sulfate against pathogen populations in poultry litters

The aim of this study was to evaluate the effects of Red Ginseng marc with alum as litter amendments on ammonia, soluble reactive phosphorus, and pathogen populations in poultry litters.

Original Source: Journal of Ginseng Research >>

Production of ginsenoside F1 using commercial enzyme Cellulase KN

The ginsenoside F1, a pharmaceutical component of ginseng, is known to have anti-aging, anti-oxidant, anti-cancer, and keratinocyte protective effects. However, the usage of ginsenoside F1 is restricted owing to the small amounts found in Korean ginseng.

Original Source: Journal of Ginseng Research >>

Rhizospheric fungi of : diversity and antagonism to host phytopathogens

Rhizospheric fungi play an essential role in plant-soil ecosystem, affect plant growth and health. In this study, we evaluated the fungal diversity in the rhizosphere of 2-year-old healthy Panax notoginseng cultivated in Wenshan, China.

Original Source: Journal of Ginseng Research >>

Leaf-specific pathogenesis-related 10 homolog, PgPR-10.3, shows binding affinity with several biologically important molecules

Pathogenesis-related (PR)-10 proteins are small, cytosolic proteins with a similar three-dimensional (3-D) structure. Crystal structures for several PR-10 homologs have similar overall folding patterns with an unusually large internal cavity that is a binding site for biologically important molecules. Although structural information on PR-10 proteins is substantial, understanding of their biological function remains limited. Here, we showed that one of the PgPR-10 homologs, PgPR-10.3, shares binding properties with flavonoids, kinetin, emodin, deoxycholic acid and ginsenoside Re (one of the steroid glycosides).

Original Source: Journal of Ginseng Research >>

Proteomic analysis of differences in amino acid metabolism between wild and cultivated

The present study aimed to compare the relative abundance of proteins and amino acid metabolites to explore the mechanisms underlying the difference between wild and cultivated ginseng (Panax ginseng Meyer) at the amino acid level.

Original Source: Journal of Ginseng Research >>

A Brief Method for the Preparation of Gintonin-Enriched Fraction from Ginseng

Ginseng has been used as a tonic for invigoration of human body. In a previous report, we identified a novel candidate responsible for the tonic role of ginseng, designated gintonin. Gintonin induces [Ca2+]i transient in animal cells via lysophosphatidic acid (LPA) receptor activation. Gintonin-mediated [Ca2+]i transient is linked to anti-Alzheimer’s disease in transgenic Alzheimer’s disease animal model. The previous method for gintonin preparation included multiple steps. The aim of this study is to develop a simple method of gintonin fraction with a high yield.

Original Source: Journal of Ginseng Research >>

Enzymatic formation of compound-K from ginsenoside Rb1 by enzyme preparation from cultured mycelia of

Minor saponins or human intestinal bacterial metabolites such as ginsenoside Rg3, F2, Rh2, and compound K are more pharmacologically active than major saponins such as ginsenoside Rb1, Rb2, and Rc. In this study, enzymatic hydrolysis of ginsenoside Rb1 was studied using enzyme preparations from cultured mycelia of mushrooms.

Original Source: Journal of Ginseng Research >>

Diversity, distribution and antagonistic activities of rhizobacteria of

Rhizobacteria play an important role in plant defense and could be promising sources of biocontrol agents. This study aimed to screen antagonistic bacteria and develop a biocontrol system for root rot complex of P. notoginseng.

Original Source: Journal of Ginseng Research >>

Comparative Phenolic Compounds Profiles and Antioxidative Activity of the Fruit, Leaves, and Roots of Korean Ginseng ( Meyer) According to Cultivation Years

Study on the phenolic compounds profiles and antioxidative activity in ginseng fruit, leaves, and roots depend on the cultivation years have been little reported so far. Hence, this study examined phenolic compounds profiles and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) free-radical-scavenging activities in the fruit, leaves, and roots of Korean ginseng (Panax ginseng Meyer) as a function of cultivation years.

Original Source: Journal of Ginseng Research >>

Changes in the ginsenoside content during the fermentation process using microbial strains

Red ginseng (RG) is processed from Panax ginseng via several methods including heat treatment, mild acid hydrolysis and microbial conversion to transform the major ginsenosides into minor ginsenosides, which have greater pharmaceutical activities. During the fermentation process using microbial strains in a machine for making red ginseng, a change of composition occurs after heating. Therefore, we confirmed that fermentation had occurred using only microbial strains and evaluated the changes in the ginsenosides and their chemical composition.

Original Source: Journal of Ginseng Research >>