Enzymatic formation of compound-K from ginsenoside Rb1 by enzyme preparation from cultured mycelia of

Minor saponins or human intestinal bacterial metabolites such as ginsenoside Rg3, F2, Rh2, and compound K are more pharmacologically active than major saponins such as ginsenoside Rb1, Rb2, and Rc. In this study, enzymatic hydrolysis of ginsenoside Rb1 was studied using enzyme preparations from cultured mycelia of mushrooms.