Furosine (ε-N-2-furoylmethyl-L-lysine, FML) is an amino acid derivative, which is considered to be an important indicator of the extent of damage (deteriorating the quality of amino acid and proteins due to a blockage of lysine and a decrease in digestibility of proteins) during the early stages of the Maillard reaction. In addition, FML has been proven to be harmful because it is closely related to a variety of diseases such as diabetes. The qualitative analysis of FML in fresh and processed ginsengs is confirmed using a high performance liquid chromatograph-mass spectrometer (HPLC-MS).
Daily Archives: 01/11/2017
Photoaging protective effects of BIOGF1K, a compound K-rich fraction prepared from
BIOGF1K, a compound K-rich fraction, has been shown to display anti-inflammatory activity. Although Panax ginseng is widely used for the prevention of photoaging events induced by ultraviolet-B (UVB) irradiation, the effect of BIOGF1K on photoaging has not yet been examined. In this study, we aimed to examine the effects of BIOGF1K on UVB-induced photoaging events.
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Ginseng and obesity
Although ginseng has been shown to have an anti-obesity effect, anti-obesity-related mechanisms are complex and have not been completely elucidated. In the present study, we evaluated ginseng’s effects on food intake, the digestion and absorption systems, as well as liver, adipose tissue, and skeletal muscle in order to identify the mechanisms involved. A review of previous in vitro and in vivo studies revealed that ginseng and ginsenosides can increase energy expenditure by stimulating the adenosine monophosphate-activated kinase pathway and can reduce energy intake.
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Efficacy and safety of berry extract on glycemic control: A 12-week randomized, double-blind, and placebo-controlled clinical trial
Anti-hyperglycemic effects of Panax ginseng berry have never been explored in humans. The aims of this study were to assess the efficacy and safety of a 12-week treatment with ginseng berry extract in subjects with a fasting glucose level between 100 and 140 mg/dL.
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Protective effect of ginsenoside Rb1 against tacrolimus-induced apoptosis in renal proximal tubular LLC-PK1 cells
The aim of the present study was to evaluate the potential protective effects of six ginsenosides (Rb1, Rb2, Rc, Rd, Rg1, and Rg3) isolated from Panax ginseng against tacrolimus (FK506)-induced apoptosis in renal proximal tubular LLC-PK1 cells.
