Tag Archives: ginseng

An optimized microwave-assisted extraction method for increasing the yields of rare ginsenosides from Panax quinquefolius L

Rare ginsenosides in Panax quinquefolius L. are proved to have stronger bioactivities. The fact that it is hard to obtain large amounts of rare ginsenosides seriously restricts further researches of rare ginsenosides. An easy, fast and efficient method to obtain amounts of different kinds of rare ginsenosides at one time and to quantify precisely of each one is in great need.

Original Source: Journal of Ginseng Research >>

Converting panax ginseng DNA and chemical fingerprint into two-dimensional barcode

In this paper, we investigate how to convert Panax ginseng DNA sequence code and chemical fingerprint into two-dimensional code. In order to improve the compression efficiency, GATC2Bytes and DMC algorithms are proposed.

Original Source: Journal of Ginseng Research >>

NF-κB- and AP-1-mediated immunostimulatory activity of Compound K in monocytes and macrophages

Compound K (CK) is a bioactive derivative from ginsenoside Rb1 in Panax ginseng (Korean ginseng). Although its biological and pharmacological activities have been studied in various disease conditions, its immunomodulatory role in innate immunity mediated by monocytes/macrophages has been poorly understood.

Original Source: Journal of Ginseng Research >>

Molecular differentiation of Russian wild ginseng using mitochondrial nad7 intron3 region

Cultivated ginseng is often introduced as substitute and adulterant of Russian wild ginseng due to its lower cost or misidentification caused by similarity in appearance with wild ginseng. The aim of this study is to develop a simple and reliable method to differentiate Russian wild ginseng from cultivated ginseng.

Original Source: Journal of Ginseng Research >>

The interaction of serum albumin with ginsenoside Rh2 (G-Rh2) resulted in the downregulation of G-Rh2 cytotoxicity

Ginsenoside Rh2 (G-Rh2) is a ginseng saponin that is widely investigated because of its remarkable antitumor activity. However, its molecular mechanism by which (20S)G-Rh2 triggers its functions and how target animals avoid its cytotoxic action remains largely unknown.

Original Source: Journal of Ginseng Research >>

Changes in element accumulation, phenolic metabolism and antioxidative enzyme activities in the red-skin roots of Panax ginseng

Red-skin root disease has seriously decreased the quality and production of Panax ginseng (ginseng).

Original Source: Journal of Ginseng Research >>

Effects of Korean ginseng berry on skin anti-pigmentation and anti-aging via FoxO3a activation

The ginseng berry has various bioactivities, including anti-diabetic, anti-cancer, anti-inflammatory, and anti-oxidative properties. Moreover, we have revealed that the active anti-aging component of the ginseng berry, syringaresinol, has the ability to stimulate longevity via gene activation. Despite the many known beneficial effects of ginseng, its effects on skin aging are poorly understood. In this study, we investigated the effects of ginseng and the ginseng berry on one of the skin aging processes, melanogenesis and age-related pigment lipofuscin accumulation, to elucidate the mechanism of action with respect to anti-aging.

Original Source: Journal of Ginseng Research >>

Identification of ginseng root using quantitative X-ray microtomgraphy

The use of X-ray phase-contrast microtomography (XPCMT) for the investigation of Chinese medicinal materials (CMMs) is advantageous for its nondestructive, in-situ and three-dimensional (3D) quantitative imaging properties.

Original Source: Journal of Ginseng Research >>

In vitro grown thickened taproots, a new type of soil transplanting source in Panax ginseng

The low survival rate of in vitro regenerated Panax ginseng plantlets after transfer to soil is the main obstacle for the successful micropropagation and molecular breeding. In most cases, young plantlets converted from somatic embryos are transferred to soil.

Original Source: Journal of Ginseng Research >>

Protective effect of Korean Red Ginseng against FK-506-induced damage in LLC-PK1 cells

Compound FK506 is an immunosuppressant agent that is frequently used to prevent rejection of solid organs upon transplant. However, nephrotoxicity due to apoptosis and inflammatory response mediated by FK506 limit its usefulness. In this study, the protective effect of Korean Red Ginseng (KRG) against FK-506-induced damage in LLC-PK1 pig kidney epithelial cells was investigated.

Original Source: Journal of Ginseng Research >>